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Takeda and Amylin to co-develop obesity drugs

1. November 2009

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Japan’s Takeda Pharmaceutical and U.S. Amylin Pharmaceuticals said on Monday they will co-develop and commercialize drugs to treat obesity, including two Amylin drugs in mid-stage trials. Takeda, Japan’s biggest drug maker and best known for its diabetes drug Actos, will pay Amylin $75 million in a one-time up-front payment under the exclusive worldwide agreement. Amylin, maker of [...]

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Orexigen obesity drug shows added benefits

24. October 2009

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Nearly half of patients who completed 56 weeks of treatment with Orexigen Therapeutics Inc’s experimental obesity treatment, Contrave, lost at least 10 percent of their weight in a late-stage study and the drug also appeared to help cholesterol and blood sugar levels. The drug demonstrated an even greater improvement in non- weight loss measures in patients [...]

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Unhooking the Obesity Diabetes Connection

26. July 2009

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SUNDAY, July 26 (HealthDay News) — Scientists may be closer to solving a medical mystery with huge implications for personal and public health: Why obese people are prone to developing type 2 diabetes. A series of studies appearing online July 26 in Nature Medicine suggest that inflammation within the fat tissues of heavy individuals could trigger [...]

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Obesity emerges as risk factor in severe flu

12. July 2009

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WASHINGTON (Reuters) – People who are obese but otherwise healthy may be at special risk of severe complications and death from the new H1N1 swine flu virus, U.S. researchers reported on Friday. They described the cases of 10 patients at a Michigan hospital who were so ill they had to be put on ventilators. Three died. [...]

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Anti-obesity product safe in mid-stage study

9. July 2009

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NEW YORK (Reuters) – Amylin Pharmaceuticals Inc said on Thursday a mid-stage study of its combination obesity product involving versions of hormones linked to appetite and metabolism yielded positive results. The Phase 2, 28-week study randomized 608 overweight or obese patients to either placebo or various doses of the product, which contains the compounds pramlintide and [...]

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Obese Get Higher Doses of Radiation for X-Rays

1. July 2009

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TUESDAY, June 30 (HealthDay News) — People who are overweight and obese are usually given higher-than-normal doses of radiation in order to obtain usable X-ray images, even though the long-term effects are unknown, new research contends. “You need to get a certain amount of X-rays to go through the body in order to get an informative [...]

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Obese Poor Shut Out From Weight-Loss Surgeries

25. June 2009

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THURSDAY, June 25 (HealthDay News) — Despite having one of the highest rates of obesity in America, the poor are less likely to undergo weight loss surgery than obese people who are better off financially, new research shows. White women with higher incomes and private health insurance were the most likely to have the surgery, according [...]

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Obesity Greatly Raises Endometrial Cancer Risk

22. June 2009

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MONDAY, June 22 (HealthDay News) — Obesity is already linked to heart disease, diabetes and high blood pressure, but new research finds those extra pounds can also significantly increase a woman’s risk of developing endometrial cancer, especially if she experiences early menopause. Published in the July issue of Obstetrics & Gynecology, the study found that women [...]

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AMA objects to calling obesity a disability

19. June 2009

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The American Medical Association has taken action to support doctors’ ability to discuss obesity with their overweight patients. Under a new policy adopted Tuesday, the AMA formally opposes efforts by advocacy groups to define obesity as a disability. Doctors fear using that definition makes them vulnerable under disability laws to lawsuits from obese patients who don’t want [...]

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Diabetes Drug Byetta Might Aid Weight Loss in Obese Patients

11. June 2009

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THURSDAY, June 11 (HealthDay News) — Exenatide (Byetta), a drug normally used to treat diabetes, may also help non-diabetic obese people lose weight when combined with diet and exercise, new research has found. Researchers divided 152 obese men and women (with a body-mass index of greater than 30 and an average weight of 241 pounds) into [...]

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